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Cells which might be poor in homologous recombination, resembling people who lack useful breast cancer-associated 1 (BRCA1) or BRCA2, are hypersensitive to inhibition of poly(ADP-ribose) polymerase (PARP). Nevertheless, BRCA-deficient tumors symbolize solely a small fraction of grownup cancers, which could limit the therapeutic utility of PARP inhibitor monotherapy. Cyclin-dependent kinase 1 (Cdk1) phosphorylates BRCA1, and that is important for environment friendly formation of BRCA1 foci. Right here we present that depletion or inhibition of Cdk1 compromises the power of cells to restore DNA by homologous recombination.

Mixed inhibition of Cdk1 and PARP in BRCA-wild-type most cancers cells resulted in decreased colony formation, delayed progress of human tumor xenografts and tumor regression with extended survival in a mouse mannequin of lung adenocarcinoma. Inhibition of Cdk1 didn’t sensitize nontransformed cells or tissues to inhibition of PARP. As a result of decreased Cdk1 exercise impaired BRCA1 operate and consequently, restore by homologous recombination, inhibition of Cdk1 represents a believable technique for increasing the utility of PARP inhibitors to BRCA-proficient cancers.

Ewing’s sarcoma household of tumors (ESFT) refers to aggressive malignancies which steadily harbor attribute EWS-FLI1 or EWS-ERG genomic fusions. Right here, we report that these fusion merchandise work together with the DNA harm response protein and transcriptional coregulator PARP-1. ESFT cells, major tumor xenografts, and tumor metastases had been all extremely delicate to PARP1 inhibition. Addition of a PARP1 inhibitor to the second-line chemotherapeutic agent temozolamide resulted in full responses of all handled tumors in an EWS-FLI1-driven mouse xenograft mannequin of ESFT.

Mechanistic investigations revealed that DNA harm induced by expression of EWS-FLI1 or EWS-ERG fusion genes was potentiated by PARP1 inhibition in ESFT cell strains. Notably, EWS-FLI1 fusion genes acted in a optimistic suggestions loop to take care of the expression of PARP1, which was required for EWS-FLI-mediated transcription, thereby implementing oncogene-dependent sensitivity to PARP-1 inhibition. Collectively, our findings provide a robust preclinical rationale to focus on the EWS-FLI1:PARP1 intersection as a therapeutic technique to enhance the therapy of ESFTs.

PARP Inhibitors for BRCA1/2 mutation-associated and BRCA-like malignancies.

Poly(ADP-ribose)polymerase inhibitors (PARPis) have proven promising exercise in sufferers with BRCA1/2 mutation-associated (BRCA1/2(MUT+)) ovarian and breast cancers. Accumulating proof means that PARPi could have a wider software within the therapy of sporadic high-grade serous ovarian most cancers, and cancers faulty in DNA restore pathways, resembling prostate, endometrial, and pancreatic cancers. A number of PARPis are at present in section 1/2 scientific investigation, with registration trials now being designed.

Olaparib, probably the most studied PARPis, has demonstrated exercise in BRCA1/2(MUT+) and BRCA-like sporadic ovarian and breast cancers, and appears promising in prostate and pancreatic cancers. Understanding extra in regards to the molecular abnormalities concerned in BRCA-like tumors, exploring novel therapeutic trial methods and drug combos, and defining potential predictive biomarkers, is crucial to quickly advancing the sector of PARPi remedy and enhance scientific outcomes.

Using the idea of artificial lethality has supplied new alternatives for the event of focused therapies, by permitting the focusing on of lack of operate genetic aberrations. In most cancers cells with BRCA1 or BRCA2 lack of operate, which harbor deficiency of DNA restore by homologous recombination, inhibition of PARP1 enzymatic exercise results in an accumulation of single strand breaks which might be transformed to double strand breaks however can’t be repaired by homologous recombination. Inhibition of PARP has subsequently been superior as a novel focused remedy for cancers harboring BRCA1/2 mutations.

Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition.

PARP inhibitors for most cancers remedy.

Poly(ADP-ribose) polymerase 1 (PARP-1) is a zinc-finger DNA-binding enzyme that’s activated by binding to DNA breaks. Poly(ADP-ribosyl)ation of nuclear proteins by PARP-1 converts DNA harm into intracellular indicators that activate both DNA restore by the base-excision pathway or cell dying. A household of 18 PARPs has been recognized, however solely essentially the most considerable, PARP-1 and PARP-2, that are each nuclear enzymes, are activated by DNA harm. PARP inhibitors of ever-increasing efficiency have been developed within the 40 years for the reason that discovery of PARP-1, each as instruments for the investigation of PARP-1 operate and as potential modulators of DNA-repair-mediated resistance to cytotoxic remedy.

Owing to the excessive stage of homology between the catalytic domains of PARP-1 and PARP-2, the inhibitors most likely have an effect on each enzymes. Convincing biochemical proof, which has been corroborated by genetic manipulation of PARP-1 exercise, reveals that PARP inhibition is related to elevated sensitivity to DNA-alkylating brokers, topoisomerase I poisons and ionising radiation. Novel PARP inhibitors of ample efficiency and appropriate pharmacokinetic properties to permit analysis in animal fashions have been proven to boost the antitumour exercise of temozolomide (a DNA-methylating agent), topoisomerase poisons and ionising radiation; certainly, the mixture with temozolomide resulted in full tumour regression in two unbiased research.

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Cancer Antigen 19-9 Antigen (Liver Carcinoma) (> 90%)

VAng-Cr3875-25kU 25 kU
EUR 738
Description: Cancer Antigen 19-9 Antigen, Host/Source: Liver Carcinoma. The purity is> 90% by SDS-PAGE. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

Gastrointestinal Cancer Antigen (CA 19-9), antigen grade

CA1991-N-10 10 KU
EUR 529

CEA (Cancer antigen) ELISA test

9 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CEA (Cancer antigen)

Cancer Antigen 19-9 Antigen (Liver Carcinoma) (High purity)

VAng-Cr3874-25kU 25 kU
EUR 861
Description: Cancer Antigen 19-9 Antigen, Host/Source: Liver Carcinoma.

Cancer Antigen CA 19-9 Antigen (Human metastatic liver carcinoma)

VAng-Wyb8635-inquire inquire Ask for price
Description: CA 19-9 (Gastrointestinal Cancer), Antigen Grade, Cancer antigen from Human metastatic liver carcinoma, 2900.0 kIU/mL.

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

DLR-CA19-9-Hu-48T 48T
EUR 441
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

DLR-CA19-9-Hu-96T 96T
EUR 570
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

RD-CA19-9-Hu-48Tests 48 Tests
EUR 436

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

RD-CA19-9-Hu-96Tests 96 Tests
EUR 601

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

RDR-CA19-9-Hu-48Tests 48 Tests
EUR 455

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

RDR-CA19-9-Hu-96Tests 96 Tests
EUR 629

Cancer Antigen CA 19-9 Antigen (Human adenocarcinoma cell line supernatant)

VAng-Wyb8634-inquire inquire Ask for price
Description: CA 19-9 (Gastrointestinal Cancer), Antigen Grade, Cancer antigen from Human adenocarcinoma cell line supernatant, 42,097 Units/mL.

Cancer Antigen CA19-9 Antibody

abx020532-1mg 1 mg
EUR 1080

Cancer Antigen CA19-9 Antibody

abx020533-1mg 1 mg
EUR 599

Cancer Antigen CA19-9 Antibody

abx020534-1mg 1 mg
EUR 599

Cancer Antigen CA19-9 Antibody

abx020535-1mg 1 mg
EUR 599

Human Cancer Tissue Preparation Buffer 19: Uterine Tumor Cells

9-80042 1 x 100 ml Ask for price

Recombinant Carbohydrate Antigen 19-9 (CA19-9)

4-RPA156Hu01
  • EUR 619.68
  • EUR 269.00
  • EUR 2048.80
  • EUR 749.60
  • EUR 1399.20
  • EUR 478.00
  • EUR 4972.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Carbohydrate Antigen 19-9 expressed in: E.coli

Carbohydrate Antigen 19-9 (CA19-9) Antibody

20-abx102715
  • EUR 314.00
  • EUR 133.00
  • EUR 815.00
  • EUR 425.00
  • EUR 272.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Carbohydrate Antigen 19-9 (CA19-9) Antibody

20-abx102716
  • EUR 300.00
  • EUR 718.00
  • EUR 384.00
  • EUR 154.00
  • EUR 244.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Cancer Tissue Preparation Buffer 9: Kidney Tumor Cells

9-80032 1 x 100 ml Ask for price

Human Carbohydrate Antigen 19-9 (CA19-9) Protein

20-abx065680
  • EUR 857.00
  • EUR 314.00
  • EUR 2750.00
  • EUR 1024.00
  • EUR 592.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Carbohydrate Antigen 19-9 (CA19-9) Antibody Pair

20-abx370223
  • EUR 1428.00
  • EUR 926.00
  • 10 × 96 tests
  • 5 × 96 tests

Carbohydrate Antigen 19-9 (CA19-9) Antibody (FITC)

20-abx273835
  • EUR 411.00
  • EUR 230.00
  • EUR 1163.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Carbohydrate Antigen 19-9 (CA19-9) Antibody (Biotin)

20-abx272438
  • EUR 453.00
  • EUR 244.00
  • EUR 1316.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Monoclonal Anti-Human Cancer Antigen 19-9 (CA199 or CA19-9) IgG # 1, aff pure

CA1991-M 1 mg
EUR 712

Human Carbohydrate Antigen 19-9 (CA19-9)CLIA Kit

SCA156Hu-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in serum, plasma other biological fluids.

Human Carbohydrate Antigen 19-9 (CA19-9)CLIA Kit

SCA156Hu-1x48wellstestplate 1x48-wells test plate
EUR 552.76
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in serum, plasma other biological fluids.

Human Carbohydrate Antigen 19-9 (CA19-9)CLIA Kit

SCA156Hu-1x96wellstestplate 1x96-wells test plate
EUR 746.8
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in serum, plasma other biological fluids.

Human Carbohydrate Antigen 19-9 (CA19-9)CLIA Kit

SCA156Hu-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in serum, plasma other biological fluids.

Human Carbohydrate Antigen 19-9 (CA19-9) CLIA Kit

4-SCA156Hu
  • EUR 5698.00
  • EUR 3061.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Carbohydrate Antigen 19-9 (CA19-9)serum, plasma other biological fluids

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

SEA156Hu-10x96wellstestplate 10x96-wells test plate
EUR 3815.2
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

SEA156Hu-1x48wellstestplate 1x48-wells test plate
EUR 401.84
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

SEA156Hu-1x96wellstestplate 1x96-wells test plate
EUR 531.2
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

SEA156Hu-5x96wellstestplate 5x96-wells test plate
EUR 2090.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

4-SEA156Hu
  • EUR 3866.00
  • EUR 2041.00
  • EUR 532.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in samples from Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Carbohydrate Antigen 19-9 (CA19-9) Polyclonal Antibody (Human)

4-PAA156Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9)

Carbohydrate Antigen 19-9 (CA19-9) Monoclonal Antibody (Human)

4-MAA156Hu21
  • EUR 226.00
  • EUR 2180.00
  • EUR 550.00
  • EUR 280.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9)

Human carbonhydrate antigen 19-9 (CA19-9) ELISA kit

CSB-E04773h-24T 1 plate of 24 wells
EUR 165
Description: Quantitative sandwich ELISA kit for measuring Human carbonhydrate antigen 19-9 (CA19-9) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human carbonhydrate antigen 19-9 (CA19-9) ELISA kit

1-CSB-E04773h
  • EUR 602.00
  • EUR 4238.00
  • EUR 2256.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human carbonhydrate antigen 19-9 (CA19-9) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Carbohydrate Antigen 19-9(CA19-9)ELISA kit

GA-E0826MS-48T 48T
EUR 336

Mouse Carbohydrate Antigen 19-9(CA19-9)ELISA kit

GA-E0826MS-96T 96T
EUR 534

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

abx050247-96tests 96 tests
EUR 621

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

abx053441-96tests 96 tests
EUR 668

Rat Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

abx256759-96tests 96 tests
EUR 754

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

abx253018-96tests 96 tests
EUR 668

Mouse Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

abx255229-96tests 96 tests
EUR 754

Human Carbohydrate Antigen 19-9 (CA19-9) CLIA Kit

20-abx190088
  • EUR 7911.00
  • EUR 4215.00
  • EUR 973.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Pig Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

abx361885-96tests 96 tests
EUR 825

Rabbit Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

abx363103-96tests 96 tests
EUR 825

Rat Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

abx350681-96tests 96 tests
EUR 668

Monkey Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

abx359969-96tests 96 tests
EUR 825

Chicken Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

abx356663-96tests 96 tests
EUR 825

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

20-abx150881
  • EUR 6173.00
  • EUR 3291.00
  • EUR 770.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Carbohydrate antigen 19 9 ELISA kit

E01C0671-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Human Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Carbohydrate antigen 19 9 ELISA kit

E01C0671-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Human Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Carbohydrate antigen 19 9 ELISA kit

E01C0671-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Human Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Carbohydrate antigen 19 9 ELISA kit

E03C0671-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Mouse Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Carbohydrate antigen 19 9 ELISA kit

E03C0671-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Mouse Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Carbohydrate antigen 19 9 ELISA kit

E03C0671-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Mouse Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Carbohydrate antigen 19 9 ELISA kit

E04C0671-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rabbit Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Carbohydrate antigen 19 9 ELISA kit

E04C0671-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rabbit Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Carbohydrate antigen 19 9 ELISA kit

E04C0671-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rabbit Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Carbohydrate antigen 19 9 ELISA kit

E02C0671-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rat Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Carbohydrate antigen 19 9 ELISA kit

E02C0671-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rat Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Carbohydrate antigen 19 9 ELISA kit

E02C0671-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rat Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Carbohydrate antigen 19 9 ELISA kit

E07C0671-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Porcine Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Carbohydrate antigen 19 9 ELISA kit

E07C0671-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Porcine Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Carbohydrate antigen 19 9 ELISA kit

E07C0671-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Porcine Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Carbohydrate antigen 19 9 ELISA kit

E08C0671-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Canine Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Carbohydrate antigen 19 9 ELISA kit

E08C0671-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Canine Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Carbohydrate antigen 19 9 ELISA kit

E08C0671-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Canine Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Carbohydrate antigen 19 9 ELISA kit

E06C0671-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Goat Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Carbohydrate antigen 19 9 ELISA kit

E06C0671-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Goat Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Carbohydrate antigen 19 9 ELISA kit

E06C0671-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Goat Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Carbohydrate antigen 19 9 ELISA kit

E09C0671-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Carbohydrate antigen 19 9 ELISA kit

E09C0671-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Carbohydrate antigen 19 9 ELISA kit

E09C0671-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Cancer Antigen 242 Antigen

VAng-Cr3876-10kU 10 kU
EUR 421
Description: Cancer Antigen 242 Antigen, Host/Source: Metastatic Liver. The purity is detected by gel filtration.

Cancer Antigen 50 Antigen

VAng-Cr3877-50kU 50 kU
EUR 5535
Description: Cancer Antigen 50 Antigen, Host/Source: Human Cell Culture. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

Human Cancer PrimaCell15: Skin Cancer Cells Growth Medium

9-46038 5 x 100 ml Ask for price

Carbohydrate Antigen 19-9 (CA19-9) Polyclonal Antibody (Human), APC

4-PAA156Hu01-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with APC.

Carbohydrate Antigen 19-9 (CA19-9) Polyclonal Antibody (Human), Biotinylated

4-PAA156Hu01-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with Biotin.

Carbohydrate Antigen 19-9 (CA19-9) Polyclonal Antibody (Human), Cy3

4-PAA156Hu01-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with Cy3.

Carbohydrate Antigen 19-9 (CA19-9) Polyclonal Antibody (Human), FITC

4-PAA156Hu01-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with FITC.

Carbohydrate Antigen 19-9 (CA19-9) Polyclonal Antibody (Human), HRP

4-PAA156Hu01-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with HRP.

Carbohydrate Antigen 19-9 (CA19-9) Polyclonal Antibody (Human), PE

4-PAA156Hu01-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with PE.

Carbohydrate Antigen 19-9 (CA19-9) Monoclonal Antibody (Human), APC

4-MAA156Hu21-APC
  • EUR 314.00
  • EUR 2825.00
  • EUR 800.00
  • EUR 395.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with APC.

Carbohydrate Antigen 19-9 (CA19-9) Monoclonal Antibody (Human), Biotinylated

4-MAA156Hu21-Biotin
  • EUR 288.00
  • EUR 2130.00
  • EUR 645.00
  • EUR 348.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with Biotin.

Carbohydrate Antigen 19-9 (CA19-9) Monoclonal Antibody (Human), Cy3

4-MAA156Hu21-Cy3
  • EUR 377.00
  • EUR 3725.00
  • EUR 1025.00
  • EUR 485.00
  • EUR 233.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with Cy3.

Carbohydrate Antigen 19-9 (CA19-9) Monoclonal Antibody (Human), FITC

4-MAA156Hu21-FITC
  • EUR 271.00
  • EUR 2280.00
  • EUR 660.00
  • EUR 336.00
  • EUR 184.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with FITC.

Carbohydrate Antigen 19-9 (CA19-9) Monoclonal Antibody (Human), HRP

4-MAA156Hu21-HRP
  • EUR 288.00
  • EUR 2465.00
  • EUR 710.00
  • EUR 359.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with HRP.

Carbohydrate Antigen 19-9 (CA19-9) Monoclonal Antibody (Human), PE

4-MAA156Hu21-PE
  • EUR 271.00
  • EUR 2280.00
  • EUR 660.00
  • EUR 336.00
  • EUR 184.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with PE.

ELISA kit for Human CA19-9 (Carbohydrate Antigen 19-9)

ELK1198 1 plate of 96 wells
EUR 372
Description: A sandwich ELISA kit for detection of Carbohydrate Antigen 19-9 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Human carbonhydrate antigen 19-9 (CA19-9)

EK0178 96 tests
EUR 712
Description: Enzyme-linked immunosorbent assay kit for quantification of Human carbonhydrate antigen 19-9 (CA19-9) in samples from serum, plasma, tissue homogenates and other biological fluids.

Human Cancer Tissue Preparation Buffer 15: Skin Cancer Cells

9-80038 1 x 100 ml Ask for price

Guinea pig Carbohydrate antigen 19 9 ELISA kit

E05C0671-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Guinea pig Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Carbohydrate antigen 19 9 ELISA kit

E05C0671-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Guinea pig Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Carbohydrate antigen 19 9 ELISA kit

E05C0671-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Guinea pig Carbohydrate antigen 19 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Carbohydrate Antigen 19-9 (CA19-9) Polyclonal Antibody (Human), APC-Cy7

4-PAA156Hu01-APC-Cy7
  • EUR 571.00
  • EUR 6430.00
  • EUR 1705.00
  • EUR 760.00
  • EUR 319.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with APC-Cy7.

Carbohydrate Antigen 19-9 (CA19-9) Monoclonal Antibody (Human), APC-Cy7

4-MAA156Hu21-APC-Cy7
  • EUR 508.00
  • EUR 5530.00
  • EUR 1480.00
  • EUR 670.00
  • EUR 292.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Carbohydrate Antigen 19-9 (CA19-9). This antibody is labeled with APC-Cy7.

Cancer Antigen 72-4 Antigen

VAng-Cr3878-10kU 10 kU
EUR 421
Description: Cancer Antigen 72-4 Antigen, Host/Source: Metastatic Liver. The purity is ~65% by SDS-PAGE. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

Human Sialylated Lewis A Antigen (CA 19-9) Antibody

30261-05111 150 ug
EUR 261

Cancer Antigen CEA Antigen (Human Fluids)

VAng-Wyb8644-inquire inquire Ask for price
Description: Carcinoembryonic Antigen, Calibrator Grade, Cancer antigen from Human Fluids, 1.13 mg/mL.

Cancer Antigen 125 Antigen (Human Adenocarcinoma)

VAng-Cr3868-10kU 10 kU
EUR 421
Description: Cancer Antigen 125 Antigen, Host/Source: Human Adenocarcinoma. The purity is detected by salt extraction and chromatography.

Cancer Antigen 125 Antigen (Ascites Fluid)

VAng-Cr3870-10kU 10 kU
EUR 944
Description: Cancer Antigen 125 Antigen, Host/Source: Ascites Fluid. The purity is ≥ 95% by SDS-PAGE.

Human Cancer PrimaCell15: Skin Cancer Cells Growth Supplements with Serum (for 500 ml medium)

9-47038 1 Set Ask for price

Human 19-9(CA19-9)ELISA

QY-E05335 96T
EUR 374

Human Cancer Antigen CA125 (Ovarian Cancer) Protein

abx061590-100kU 100 kU
EUR 1205

CA 19-9 protein

30C-CP9063S 25 KU
EUR 138
Description: Purified CA 19-9 protein

CA 19-9 protein

30-1067 25 KU
EUR 610
Description: Purified native Human CA 19-9 protein

CA 19-9 protein

30-AC09 50 KU
EUR 310
Description: Cell culture concentrate of Human CA 19-9 protein

CA 19-9 protein

30-AC15 50 KU
EUR 408
Description: Purified native Human CA 19-9 protein

CA 19-9 protein

30-AC15S 50 KU
EUR 352
Description: Partially purified Human CA 19-9 protein

CA 19-9 protein

30-AC33 50 KU
EUR 457
Description: Cell culture concentrate of Human CA 19-9 protein

CA 19-9 antibody

10-1148 250 ug
EUR 245
Description: Mouse monoclonal CA 19-9 antibody

CA 19-9 antibody

10-C04E 1 mg
EUR 291
Description: Mouse monoclonal CA 19-9 antibody

CA 19-9 antibody

10-CA19A 1 mg
EUR 565
Description: Mouse monoclonal CA 19-9 antibody

CA 19-9 antibody

10R-6760 1 ml
EUR 402
Description: Mouse monoclonal CA 19-9 antibody

1116-NS-19-9

C0033006 One Frozen vial
EUR 543

Human Cancer PrimaCell7: Esophageal Fibroblasts Growth Medium

9-46030 5 x 100 ml Ask for price

Human Cancer PrimaCell8: Glioma Cells Growth Medium

9-46031 5 x 100 ml Ask for price

Individual Reaction Mix 9

G065-9 200 reactions
EUR 167

7095B 9 PASTEUR PIPET

7095B-9 200/pk
EUR 70
Description: Disposable Pipets; Pasteur Pipets

Cancer Antigen AFP Antigen (Human Cord Blood)

VAng-Wyb8624-inquire inquire Ask for price
Description: Alpha Fetoprotein (66 kDa), Cancer antigen from Human Cord Blood, 1.73 mg/mL.

Cancer Antigen AFP Antigen (Human hepatocellular carcinoma)

VAng-Wyb8625-inquire inquire Ask for price
Description: Alpha Fetoprotein, Antigen Grade, Cancer antigen from human hepatocellular carcinoma, 2.93 mg/mL.

Cancer Antigen CA-125 Antigen (Human Fluids)

VAng-Wyb8639-inquire inquire Ask for price
Description: CA-125, Calibrator Grade, cancer antigen from Human Fluids, 53.26 KU/mL.

Cancer Antigen CA-125 Antigen (Human Adenocarcinoma)

VAng-Wyb8642-inquire inquire Ask for price
Description: CA-125, Calibrator Grade, Cancer antigen from Human Adenocarcinoma, 500 kIU / mL.

Cancer Antigen CEA Antigen (Human Metastatic Liver)

VAng-Wyb8645-inquire inquire Ask for price
Description: Carcinoembryonic Antigen, Antigen Grade, Cancer antigen from Human Metastatic Liver, 5.5 mg/mL.

Cancer Antigen 125 Antigen (Human Adenocarcinoma) (> 90%)

VAng-Cr3869-25kU 25 kU
EUR 806
Description: Cancer Antigen 125 Antigen, Host/Source: Human Adenocarcinoma. The purity is> 90% by SDS-PAGE. Matched Pair: HM183, HM184, HM185, HM186.

Human Cancer PrimaCell1: Esophageal Tumor Cells Growth Medium

9-46024 5 x 100 ml Ask for price

Human Cancer PrimaCell3: Bladder Tumor Cells Growth Medium

9-46026 5 x 100 ml Ask for price

The mixture of a PARP inhibitor and temozolomide is at present present process scientific analysis for the primary time. Preclinical and preliminary scientific proof, nonetheless, suggests a probably broader scope for PARP inhibitors. Lack of operate of assorted proteins concerned in double strand break restore aside from BRCA1/2 has been urged to be synthetically deadly with PARP inhibition. Inactivation of those genes has been reported in a subset of human cancers and would possibly subsequently represent predictive biomarkers for PARP inhibition. Right here we focus on the proof that the scientific use of PARP inhibition could also be broader than focusing on of cancers in BRCA1/2 germ-line mutation carriers.